Dexamethasone is a corticosteroid that is used to treat different heath conditions such as skin diseases, allergic disorder, asthma, brain swelling, rheumatic problems and arthritis.
This drug comes in various trade names like Decadron, Dexasone, Diodex, Hexadrol, Maxidex, DexPak, Zema-Pak, etc.. It reduces the defensive response of the body and reduces symptoms. It can be administered with antibiotics to treat tuberculosis.
Dexamethasone is administered into the body system through the following means:
Intravenous Therapy: When the medicine in liquid form, it is administered to the body by shipping through the vein with the aid of injections or as drips. This mode of administration is known to be the fastest as it goes directly to the bloodstream.
Intramuscular therapy: Otherwise known and abbreviated as IM. This drug delivery system is done by the aid of injection into the muscle.
Subcutaneous Injection Therapy: is one of the many method of drug administration. It is abbreviated as SC and is used to administration dexamethasone during the subcutaneous layer of the skin.
Oral Administration: This involves administering dexamethasone throughout the mouth.
Dexamethasone Tablets USP generally contain either 0.5 mg, 0.75 mg, 1.5 mg, 2 mg, 4 mg, or 6 mg of dexamethasone USP. Each tablet also contain some inactive ingredients such as magnesium stearate, lactose, monohydrate, sugar, starch, FDamp;C Red, FDamp;C Yellow, Yellow Iron Oxide, Damp;C Yellow, and FDamp;C Blue.
Dexamethasone Oral Solution USP is formulated for oral administration contains 05.5 mg per 5 ml of dexamethasone USP. This oral solution contains some inactive ingredients such as propylene glycol, sorbitol solution, propylparaben, anhydrous citric acid, glycerin, disodium edetate and water.
USES OF DEXAMETHASONE/PROS
Dexamethasone has various uses in anti inflammatory diseases, cancer, endocrine therapy, pregnancy, high altitude illnesses, nausea and vomiting, sore throat, and veterinary uses.
Dexamethasone is combined with clotrimazole and marbofloxacin using a brand name AURIZON as a treatment for severe earing infections especially in puppies.
Dexamethasone combined with dichlormethiazide may be used to treat general bruising and swelling distal limbs in horses.
A single dose of dexamethasone in children reduces the swelling of the airway which in turns improves breathing and decreased discomfort. In other words, can be used for treating CROUP in children. Dexamethasone given in a high dose serves as a counteract to allergic anaphylactic shock, Dexamethasone intravitreal steroid implant has been accepted by the Federal dental agency for the treatment of climatic conditions such as diabetic macular edema, central retinal vein occlusion, and uveitis, dexamethasone is present in ear drops, eye drops especially after eye surgery and present in nasal sprays. Dexamethasone is used to treat autoimmune and inflammatory diseases such as rheumatoid arthritis, Idiopathic thrombocytopenic purpura. Dexamethasone is given before and or after dental surgeries like the elimination of the wisdom tooth. Dexamethasone may also be administered before antibiotics in the event of bacterial meningitis to reduce inflammatory response to the killed bacterias.
In brain tumors, dexamethasone can be used to suppress the development of edema which can compress other brain structures if not attended to, dexamethasone can be utilised as a direct chemotherapeutic agent for the treatment of multiple myeloma.
Pregnancy complications may happen like premature delivery, but with the use of dexamethasone, it can help correct premature delivery by helping in the maturation of the fetus' lungs.
Nausea and vomiting
People who have had surgery experience nausea and vomiting. Administration of dexamethasone intravenously is effective for the prevention of nausea and vomiting from recurring.
Dexamethasone, like every other drugs has side effects they provide. The Normal side effects from the consumption of dexamethasone includes
Trouble in sleeping
Increase in appetite
But if the below listed serious side effects take place, contact your doctor as soon as you notice
Increased thirst and urination
Signs of infection like fever
Slow, fast or irregular heartbeat
For those who have a fungal infection or allergic to this drug, please do not take it. Before taking dexamethasone, tell your doctor or pharmacist if you have:
Glaucoma or cataracts
High blood pressure
Herpes infection of the eyes
This medication may mask signs of infection or put you at greater risk of developing very serious ailments. Report any injuries or signs of infection (e.g., persistent sore throat/fever/cough, pain during urination, muscle aches) that occur during treatment.
This medicine may slow down a child's growth if used for a long time. Consult the doctor or pharmacist for additional information. See the doctor regularly so your child's height and growth could be assessed.
This drug may pass into breast milk and could have undesirable effects on a nursing infant. Consult your doctor before breast- feeding.
An overdose of this medication doesn't pose any life-threatening issues. Long term use of high does may lead to thinning skin, increased acne or facial hair, loss of interest in sex, menstrual problems and impotence.
DRUGS THAT AFFECT DEXAMETHASONE
It's not a fantastic safe to use some specific drugs at exactly the same time since they pose a great deal of risks. Ensure you tell your doctor about all the drugs you are using before taking dexamethasone for example;
Insulin or diabetes medications
Birth control pills or hormone replacement therapy
Blood thinner -- Coumadin, Jantoven
Antibiotic or antifungal medicine
Medication to treat dementia or Parkinson disease
The action of the world health organization in tagging dexamethasone as an essential drug in the medical field has revealed dexamethasone to be of relevance to the health of man and studies showing that surplus dexamethasone can cause hypertension through various mechanisms demonstrate that where there is good, there's also bad. Moderation is the key to ensuring that more good than bad is what has gotten from this drug. Following the physician's prescription strictly and not self-medicating will also help to make dexamethasone us be of more good than bad.
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